The San Francisco 49ers have suffered in one key area without running back Christian McCaffrey to start the 2024 NFL season.

The 49ers signed linebacker De'Vondre Campbell to a one-year, $5 million deal to fill in while Dre Greenlaw works his way ...

The town of Newport in East Tennessee was evacuated as the nearby Walters Dam was experiencing imminent failure, as remnants ...

After missing the first three games of the season, San Francisco 49ers star running back Christian McCaffrey is set to ramp ...

The damage from the storm has been extensive across the Miami Valley, with large amounts of debris scattered. NFL News: 49ers ...

San Francisco 49ers wide receiver Deebo Samuel was inactive in Week 3 against the Los Angeles Rams with a calf strain injury. Samuel suffered the injury in the ...

The San Francisco 49ers got mixed injury news, with star receiver Deebo Samuel practicing for a second straight day and ...

The first order of business right now for the San Francisco 49ers is to get healthy so they will have enough horses to ...

And Purdy would pass this test with flying colors, throwing for 292 yards and three touchdowns, ultimately losing the game 27-24 to the Los Angeles Rams. Fortunately, the 49ers should be getting some ...

The potential returns of George Kittle and Deebo Samuel could help the 49ers offense reach a next gear against ...

The 49ers are extremely hopeful about rookie running back Isaac Guerendo. He's a bit of a project considering he never started a game in college.

The San Francisco 49ers' rocky start has set off alarm bells, despite many of their issues appearing fixable with 14 games left on the schedule.