When scanning the Premier League calendar for potential 'game of the week' candidates this summer, we were quick to highlight Man United versus Tottenham Hotspur as our headliner for Matchday 6.

Tottenham were able to name only a 23-man squad for the Europa League because of a shortage of homegrown players – will that hinder them?

Even though both English giants are off to a slow start in the Premier League, this is the biggest matchup of Game Week 6. Both Manchester United and Tottenham Hotspurs only have seven points in five games so far and another loss would push them further down in the bottom half of the table.

Undefeated Arsenal will be hoping that their Premier League fixture list is finely starting to ease as they welcome winless Leicester City to the Emirates Stadium on Saturday afternoon. Mikel Arteta's side are unbeaten through their opening five matches,

Follow live coverage as Arsenal face Leicester City today in the Premier League. Another top-flight season will be covered in full right here with The Independent, as reigning champions Manchester City look to make it an unprecedented five titles in a row come the end of 2024/25.