A widespread artifact in bacterial chemical genomics caused by uncorrected differences in growth causes spurious correlations ...
The Krebs cycle byproduct itaconate regulates immune cell function, however its role within tumor cells remains unclear. Here ...
Fibrosis and accumulation of senescent cells are common tissue changes associated with aging. Here, we show that the CDK ...
In this issue, Papismadov et al (2024) report that p21 (CDKN1A), known to activate the senescence growth arrest, also ...
The systemic regulation of metabolic dysfunction-associated liver disease remains poorly understood. In this issue, Hsiao et al (2024) identify PCPE-1 as a brown-adipose tissue-derived mediator of ...
Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. The precise organization of pre- and ...
Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Evidence suggests mitochondrial homeostasis ...
Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Protein copy numbers constrain systems-level ...
Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. The intracellular bacterial pathogen Coxiella ...